Time to diagnosis in younger-onset dementia and the impact of a specialist diagnostic service.
Identifieur interne : 000051 ( Main/Exploration ); précédent : 000050; suivant : 000052Time to diagnosis in younger-onset dementia and the impact of a specialist diagnostic service.
Auteurs : Samantha M. Loi [Australie] ; Anita M Y. Goh [Australie] ; Ramon Mocellin [Australie] ; Charles B. Malpas [Australie] ; Shaun Parker [Australie] ; Dhamidhu Eratne [Australie] ; Sarah Farrand [Australie] ; Wendy Kelso [Australie] ; Andrew Evans [Australie] ; Mark Walterfang [Australie] ; Dennis Velakoulis [Australie]Source :
- International psychogeriatrics [ 1741-203X ] ; 2020.
Abstract
OBJECTIVES
While early diagnosis of younger-onset dementia (YOD) is crucial in terms of accessing appropriate services and future planning, diagnostic delays are common. This study aims to identify predictors of delay to diagnosis in a large sample of people with YOD and to investigate the impact of a specialist YOD service on this time to diagnosis.
DESIGN
A retrospective cross-sectional study.
SETTING
The inpatient unit of a tertiary neuropsychiatry service in metropolitan Victoria, Australia.
PARTICIPANTS
People diagnosed with a YOD.
MEASUREMENTS AND METHODS
We investigated the following predictors using general linear modeling: demographics including sex and location, age at onset, dementia type, cognition, psychiatric diagnosis, and number of services consulted with prior to diagnosis.
RESULTS
A total of 242 inpatients were included. The mean time to diagnosis was 3.4 years. Significant predictors of delay included younger age at onset, dementia type other than Alzheimer's disease (AD) and behavioral-variant frontotemporal dementia (bvFTD), and increased number of services consulted. These predictors individually led to an increased diagnostic delay of approximately 19 days, 5 months, and 6 months, respectively. A specialized YOD service reduced time to diagnosis by 12 months.
CONCLUSION
We found that younger age at onset, having a dementia which was not the most commonly occurring AD or bvFTD, and increasing number of services were significant predictors of diagnostic delay. A novel result was that a specialist YOD service may decrease diagnostic delay, highlighting the importance of such as service in reducing time to diagnosis as well as providing post-diagnostic support.
DOI: 10.1017/S1041610220001489
PubMed: 32854788
Affiliations:
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wicri:level="1"><nlm:affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, Monash University, Clayton, Victoria3168, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Psychology, Monash University, Clayton, Victoria3168</wicri:regionArea><wicri:noRegion>Victoria3168</wicri:noRegion></affiliation></author><author><name sortKey="Evans, Andrew" sort="Evans, Andrew" uniqKey="Evans A" first="Andrew" last="Evans">Andrew Evans</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation></author><author><name sortKey="Walterfang, Mark" sort="Walterfang, Mark" uniqKey="Walterfang M" first="Mark" last="Walterfang">Mark Walterfang</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, 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Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052</wicri:regionArea><wicri:noRegion>Victoria3052</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32854788</idno><idno type="pmid">32854788</idno><idno 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Loi</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052</wicri:regionArea><wicri:noRegion>Victoria3052</wicri:noRegion></affiliation></author><author><name sortKey="Goh, Anita M Y" sort="Goh, Anita M Y" uniqKey="Goh A" first="Anita M Y" last="Goh">Anita M Y. Goh</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052</wicri:regionArea><wicri:noRegion>Victoria3052</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>National Ageing Research Institute, Poplar Road, Parkville, Victoria3052, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>National Ageing Research Institute, Poplar Road, Parkville, Victoria3052</wicri:regionArea><wicri:noRegion>Victoria3052</wicri:noRegion></affiliation></author><author><name sortKey="Mocellin, Ramon" sort="Mocellin, Ramon" uniqKey="Mocellin R" first="Ramon" last="Mocellin">Ramon Mocellin</name><affiliation wicri:level="1"><nlm:affiliation>Delmont Private Hospital, Glen Iris, Victoria3146, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Delmont Private Hospital, Glen Iris, Victoria3146</wicri:regionArea><wicri:noRegion>Victoria3146</wicri:noRegion></affiliation></author><author><name sortKey="Malpas, Charles B" sort="Malpas, Charles B" uniqKey="Malpas C" first="Charles B" last="Malpas">Charles B. Malpas</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Outcomes Research Unit, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Clinical Outcomes Research Unit, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation></author><author><name sortKey="Parker, Shaun" sort="Parker, Shaun" uniqKey="Parker S" first="Shaun" last="Parker">Shaun Parker</name><affiliation wicri:level="1"><nlm:affiliation>Monash Health, Clayton, Victoria3169, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash Health, Clayton, Victoria3169</wicri:regionArea><wicri:noRegion>Victoria3169</wicri:noRegion></affiliation></author><author><name sortKey="Eratne, Dhamidhu" sort="Eratne, Dhamidhu" uniqKey="Eratne D" first="Dhamidhu" last="Eratne">Dhamidhu Eratne</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052</wicri:regionArea><wicri:noRegion>Victoria3052</wicri:noRegion></affiliation></author><author><name sortKey="Farrand, Sarah" sort="Farrand, Sarah" uniqKey="Farrand S" first="Sarah" last="Farrand">Sarah Farrand</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation></author><author><name sortKey="Kelso, Wendy" sort="Kelso, Wendy" uniqKey="Kelso W" first="Wendy" last="Kelso">Wendy Kelso</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, Monash University, Clayton, Victoria3168, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Psychology, Monash University, Clayton, Victoria3168</wicri:regionArea><wicri:noRegion>Victoria3168</wicri:noRegion></affiliation></author><author><name sortKey="Evans, Andrew" sort="Evans, Andrew" uniqKey="Evans A" first="Andrew" last="Evans">Andrew Evans</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation></author><author><name sortKey="Walterfang, Mark" sort="Walterfang, Mark" uniqKey="Walterfang M" first="Mark" last="Walterfang">Mark Walterfang</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052</wicri:regionArea><wicri:noRegion>Victoria3052</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Florey Institute of Neuroscience and Mental Health, Parkville, Victoria3052, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Florey Institute of Neuroscience and Mental Health, Parkville, Victoria3052</wicri:regionArea><wicri:noRegion>Victoria3052</wicri:noRegion></affiliation></author><author><name sortKey="Velakoulis, Dennis" sort="Velakoulis, Dennis" uniqKey="Velakoulis D" first="Dennis" last="Velakoulis">Dennis Velakoulis</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050</wicri:regionArea><wicri:noRegion>Victoria3050</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052</wicri:regionArea><wicri:noRegion>Victoria3052</wicri:noRegion></affiliation></author></analytic><series><title level="j">International psychogeriatrics</title><idno type="eISSN">1741-203X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVES</b></p><p>While early diagnosis of younger-onset dementia (YOD) is crucial in terms of accessing appropriate services and future planning, diagnostic delays are common. This study aims to identify predictors of delay to diagnosis in a large sample of people with YOD and to investigate the impact of a specialist YOD service on this time to diagnosis.</p></div><div type="abstract" xml:lang="en"><p><b>DESIGN</b></p><p>A retrospective cross-sectional study.</p></div><div type="abstract" xml:lang="en"><p><b>SETTING</b></p><p>The inpatient unit of a tertiary neuropsychiatry service in metropolitan Victoria, Australia.</p></div><div type="abstract" xml:lang="en"><p><b>PARTICIPANTS</b></p><p>People diagnosed with a YOD.</p></div><div type="abstract" xml:lang="en"><p><b>MEASUREMENTS AND METHODS</b></p><p>We investigated the following predictors using general linear modeling: demographics including sex and location, age at onset, dementia type, cognition, psychiatric diagnosis, and number of services consulted with prior to diagnosis.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>A total of 242 inpatients were included. The mean time to diagnosis was 3.4 years. Significant predictors of delay included younger age at onset, dementia type other than Alzheimer's disease (AD) and behavioral-variant frontotemporal dementia (bvFTD), and increased number of services consulted. These predictors individually led to an increased diagnostic delay of approximately 19 days, 5 months, and 6 months, respectively. A specialized YOD service reduced time to diagnosis by 12 months.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>We found that younger age at onset, having a dementia which was not the most commonly occurring AD or bvFTD, and increasing number of services were significant predictors of diagnostic delay. A novel result was that a specialist YOD service may decrease diagnostic delay, highlighting the importance of such as service in reducing time to diagnosis as well as providing post-diagnostic support.</p></div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32854788</PMID><DateRevised><Year>2020</Year><Month>08</Month><Day>28</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1741-203X</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Aug</Month><Day>28</Day></PubDate></JournalIssue><Title>International psychogeriatrics</Title><ISOAbbreviation>Int Psychogeriatr</ISOAbbreviation></Journal><ArticleTitle>Time to diagnosis in younger-onset dementia and the impact of a specialist diagnostic service.</ArticleTitle><Pagination><MedlinePgn>1-9</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1017/S1041610220001489</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">While early diagnosis of younger-onset dementia (YOD) is crucial in terms of accessing appropriate services and future planning, diagnostic delays are common. This study aims to identify predictors of delay to diagnosis in a large sample of people with YOD and to investigate the impact of a specialist YOD service on this time to diagnosis.</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">A retrospective cross-sectional study.</AbstractText><AbstractText Label="SETTING" NlmCategory="METHODS">The inpatient unit of a tertiary neuropsychiatry service in metropolitan Victoria, Australia.</AbstractText><AbstractText Label="PARTICIPANTS" NlmCategory="METHODS">People diagnosed with a YOD.</AbstractText><AbstractText Label="MEASUREMENTS AND METHODS" NlmCategory="METHODS">We investigated the following predictors using general linear modeling: demographics including sex and location, age at onset, dementia type, cognition, psychiatric diagnosis, and number of services consulted with prior to diagnosis.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 242 inpatients were included. The mean time to diagnosis was 3.4 years. Significant predictors of delay included younger age at onset, dementia type other than Alzheimer's disease (AD) and behavioral-variant frontotemporal dementia (bvFTD), and increased number of services consulted. These predictors individually led to an increased diagnostic delay of approximately 19 days, 5 months, and 6 months, respectively. A specialized YOD service reduced time to diagnosis by 12 months.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">We found that younger age at onset, having a dementia which was not the most commonly occurring AD or bvFTD, and increasing number of services were significant predictors of diagnostic delay. A novel result was that a specialist YOD service may decrease diagnostic delay, highlighting the importance of such as service in reducing time to diagnosis as well as providing post-diagnostic support.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Loi</LastName><ForeName>Samantha M</ForeName><Initials>SM</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-4953-4500</Identifier><AffiliationInfo><Affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goh</LastName><ForeName>Anita M Y</ForeName><Initials>AMY</Initials><AffiliationInfo><Affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>National Ageing Research Institute, Poplar Road, Parkville, Victoria3052, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mocellin</LastName><ForeName>Ramon</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Delmont Private Hospital, Glen Iris, Victoria3146, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Malpas</LastName><ForeName>Charles B</ForeName><Initials>CB</Initials><AffiliationInfo><Affiliation>Clinical Outcomes Research Unit, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Parker</LastName><ForeName>Shaun</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Monash Health, Clayton, Victoria3169, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eratne</LastName><ForeName>Dhamidhu</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Farrand</LastName><ForeName>Sarah</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kelso</LastName><ForeName>Wendy</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, Monash University, Clayton, Victoria3168, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walterfang</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Florey Institute of Neuroscience and Mental Health, Parkville, Victoria3052, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Velakoulis</LastName><ForeName>Dennis</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Neuropsychiatry, NorthWestern Mental Health, Royal Melbourne Hospital, Parkville, Victoria3050, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Grattan Street, Parkville, Victoria3052, Australia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>08</Month><Day>28</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Int Psychogeriatr</MedlineTA><NlmUniqueID>9007918</NlmUniqueID><ISSNLinking>1041-6102</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">diagnosis</Keyword><Keyword MajorTopicYN="N">neuropsychiatry</Keyword><Keyword MajorTopicYN="N">younger-onset dementia</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>8</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>8</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>8</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32854788</ArticleId><ArticleId IdType="pii">S1041610220001489</ArticleId><ArticleId IdType="doi">10.1017/S1041610220001489</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li></country></list><tree><country name="Australie"><noRegion><name sortKey="Loi, Samantha M" sort="Loi, Samantha M" uniqKey="Loi S" first="Samantha M" last="Loi">Samantha M. Loi</name></noRegion><name sortKey="Eratne, Dhamidhu" sort="Eratne, Dhamidhu" uniqKey="Eratne D" first="Dhamidhu" last="Eratne">Dhamidhu Eratne</name><name sortKey="Eratne, Dhamidhu" sort="Eratne, Dhamidhu" uniqKey="Eratne D" first="Dhamidhu" last="Eratne">Dhamidhu Eratne</name><name sortKey="Evans, Andrew" sort="Evans, Andrew" uniqKey="Evans A" first="Andrew" last="Evans">Andrew Evans</name><name sortKey="Farrand, Sarah" sort="Farrand, Sarah" uniqKey="Farrand S" first="Sarah" last="Farrand">Sarah Farrand</name><name sortKey="Goh, Anita M Y" sort="Goh, Anita M Y" uniqKey="Goh A" first="Anita M Y" last="Goh">Anita M Y. Goh</name><name sortKey="Goh, Anita M Y" sort="Goh, Anita M Y" uniqKey="Goh A" first="Anita M Y" last="Goh">Anita M Y. Goh</name><name sortKey="Goh, Anita M Y" sort="Goh, Anita M Y" uniqKey="Goh A" first="Anita M Y" last="Goh">Anita M Y. Goh</name><name sortKey="Kelso, Wendy" sort="Kelso, Wendy" uniqKey="Kelso W" first="Wendy" last="Kelso">Wendy Kelso</name><name sortKey="Kelso, Wendy" sort="Kelso, Wendy" uniqKey="Kelso W" first="Wendy" last="Kelso">Wendy Kelso</name><name sortKey="Loi, Samantha M" sort="Loi, Samantha M" uniqKey="Loi S" first="Samantha M" last="Loi">Samantha M. Loi</name><name sortKey="Malpas, Charles B" sort="Malpas, Charles B" uniqKey="Malpas C" first="Charles B" last="Malpas">Charles B. Malpas</name><name sortKey="Malpas, Charles B" sort="Malpas, Charles B" uniqKey="Malpas C" first="Charles B" last="Malpas">Charles B. Malpas</name><name sortKey="Mocellin, Ramon" sort="Mocellin, Ramon" uniqKey="Mocellin R" first="Ramon" last="Mocellin">Ramon Mocellin</name><name sortKey="Parker, Shaun" sort="Parker, Shaun" uniqKey="Parker S" first="Shaun" last="Parker">Shaun Parker</name><name sortKey="Velakoulis, Dennis" sort="Velakoulis, Dennis" uniqKey="Velakoulis D" first="Dennis" last="Velakoulis">Dennis Velakoulis</name><name sortKey="Velakoulis, Dennis" sort="Velakoulis, Dennis" uniqKey="Velakoulis D" first="Dennis" last="Velakoulis">Dennis Velakoulis</name><name sortKey="Walterfang, Mark" sort="Walterfang, Mark" uniqKey="Walterfang M" first="Mark" last="Walterfang">Mark Walterfang</name><name sortKey="Walterfang, Mark" sort="Walterfang, Mark" uniqKey="Walterfang M" first="Mark" last="Walterfang">Mark Walterfang</name><name sortKey="Walterfang, Mark" sort="Walterfang, Mark" uniqKey="Walterfang M" first="Mark" last="Walterfang">Mark Walterfang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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